PERFORM closed in June 2021
Over its lifecycle (2016 - 2021) PERFORM developed a comprehensive management plan for febrile patients, capable of being implemented across different health-care systems in Europe, linking sophisticated new genomic and proteomic approaches to clinical phenotyping.
Further outputs from the project, including publications and public deliverables are updated via the Publications page and the Public Deliverables page.
The final stakeholder engagement event was presented by the PERFORM consortium on 29th June 2021, a recording of the event can be viewed below.
The consortium and their research continues in PERFORM's sister-project DIAMONDS (Diagnosis and Management of Febrile Illness using RNA Personalised Molecular Signature Diagnosis).
Head to the DIAMONDS website, and follow @DIAMONDS_2020 on Twitter to keep up to date with all the latest news from the consortium.
Publications
Integrated Chemometrics and Statistics to Drive Successful Proteomics Biomarker Discovery. (2018). Suppers, A., van Gool, A. & Wessels, W. Proteomes. DOI: 10.3390/proteomes6020020
A comparison of clinical paediatric guidelines for hypotension with population-based lower centiles: a systematic review. Hagedoorn, N.N, Zachariasse, J.M. & A.
A NICE combination predicting hospitalisation at triage. Borensztajn, D., Hagedoorn, N., von Both, U., Carrol, E.D., Dewez, M., Emonts, M., van der Flier, M., de Groot, R., Herberg, J., Kohlmaier, B., Lim, E., Maconochie, I., Federico Martinón-Torres, F., Nijman, R., Pokorn, M., Strle, F., Tsolia, M., Vermont, C., Yeung, S., Zavadska, D., Zenz, W., Levin, M. & Moll, H.A.
Clinical Characteristics of 58 Children With a Pediatric Inflammatory Multisystem Syndrome Temporally Associated With SARS-CoV2. 2020. Whittaker, E., Bamford, A., Kenny, J., Kaforou, M., Jones, C.E., Shah, P., Ramnarayan, P., Fraisse, A., Miller, O., Davies, P., Kucera, F., Brierley, J., McDougall, M., Carter, M., Tremoulet, A., Shimizu, C., Herberg, J., Burns, J.C., Lyall, H. & Michael Levin. JAMA. DOI: 10.1001/jama.2020.10369
Diversity in the emergency care for febrile children in Europe: a questionnaire study. 2019. Borensztajn, D., Yeung, S., Hagedoorn, N.N., Balode, A., von Both, U. and Carrol, E.D. BMJ Paediatr Open, 3(1): e000456.DOI: 10.1136/bmjpo-2019-000456
Clinical practice guidelines for acute otitis media in children: a systematic review and appraisal of European national guidelines. (2020). Suzuki, H.G., Dewez, J.E., Nijman, R.G. & Yeung, S. BMJ. DOI: 10.1136/bmjopen-2019-035343
The cost of diagnostic uncertainty: a prospective economic analysis of febrile children attending an NHS emergency department (2019) Leigh, S., Grant, A., Murray, N., Faragher, B., Desai, H., Dolan, S., Cabdi, N.
